Timothy Winey
Wednesday, May 3, 2023
According to Bobo Feng et al., small changes in water properties can delicately control the binding process of DNA and thus directly affect genomic stability.
‘DNA strand exchange is catalyzed by molecular crowding and hydrophobic interactions in concentrated aqueous solutions of polyethylene glycol, a discovery of relevance for understanding the function of recombination enzymes and with potential applications to DNA nanotechnology. © 2010 The Royal Society of Chemistry.’
A solution of Sodium Alginate was prepared by high speed mixing, then split. One sample (left) was exposed to a torsion field for 20 minutes before adding dissolved Borax (with green food coloring for contrast) to both samples.
After 72 hours, large, distinct crystal structures can be observed covering the entirety of the experimental bottle (left) with no observable crystallization in the control bottle (right). This was the 2nd such experiment with this surprising result. The first experiment used the same 2 bottles in reverse order (switched). One possible explanation is that the torsion field-exposed alginate more successfully ‘excluded’ the green borax solution (hydrophobic effect), maintaining a higher concentration of borax. In hundreds of such experiments not involving alginates, crystals never failed to form. There appears to be a qualitative difference between the miscibility of these two samples, a difference I believe warrants more thorough investigation and replication. Since alginates are so widely used as tissue mimics, the biological significance of such a difference in crystallization rate should, I imagine, not be lost on the uninitiated.
Concepts such as energy, information, their relation to each other (Maxwell Demon), chirality, quantum electrodynamics, zero point energy, hidden variables (Bohmian mechanics), all come to mind. Some have even posited theories of aging revolving around a loss of homochirality and presumably, increased entropy. If torsion fields enable crystallization in the presence of alginates through a process of increased chirality (and concomitant reduced entropy), then perhaps it’s not unreasonable to expect that aging and disease may be influenced by such fields.
References:
1. https://journals.aps.org/prb/abstract/10.1103/PhysRevB.96.075305
2. https://physicsworld.com/a/maxwells-demon-tamed/
3. https://onlinelibrary.wiley.com/doi/full/10.1002/chir.23423
4. https://www.researchgate.net/publication/314433542_A_chiral_Maxwell_Demon
5. https://hms.harvard.edu/news/loss-epigenetic-information-can-drive-aging-restoration-can-reverse
6. https://link.springer.com/article/10.1007/s40140-021-00498-7
7. https://www.simsoup.info/Origin_Issues_Homochirality.html
8. https://www.levelshealth.com/blog/new-research-shows-loss-of-epigenetic-information-can-drive-aging